Cathepsin Probes

ActivX has developed cathepsin probes based on the acyloxymethyl ketone motif containing either fluorescent or desthiobiotin tags. The probes are cell-permeable and can be used to profile cathepsins or cathepsin inhibitors in either lysates or live cells.

Cathepsin probe coverage

Profiling cathepsins in various proteomes by XSite™ (LC-MS2):

Profiling cathepsins in various proteomes by XSite™ (LC-MS2)

Profiling a cathepsin inhibitor in live cells

Profiling a cathepsin inhibitor in live HepG2 cells with the flourescent cathepsin probe by Xhibit™ (SDS-PAGE):

Profiling a cathepsin inhibitor in live HepG2 cells with the flourescent cathepsin probe by Xhibit™ (SDS-PAGE)

 

Contact KiNativ™Contact ActivX

For more information about ActivX Targeted Probes or profiling needs please contact us.

ActivX Biosciences, Inc.
Telephone: (858) 526-2515
Fax: (858) 587-4878

Probes available from Thermo Scientific